Alistrol works through a sophisticated, multi-pathway synergistic mechanism that addresses the root causes of hypertension while providing comprehensive whole-body benefits. Its clinically validated, plant-based formula, grown on CLE Holistic Health's own organic Canadian farms, targets cardiovascular health from four critical angles simultaneously:

The active compound trigonelline stimulates endothelial nitric oxide synthase (eNOS) via phosphorylation of Ser1177, triggered by elevated intracellular calcium. This increases nitric oxide (NO) production, which relaxes and dilates blood vessels, reducing peripheral resistance and
significantly improving blood flow to the heart and throughout the body. This enhanced circulation delivers vital oxygen and nutrients to every organ, including the brain, supporting cognitive function and mental clarity.
Scientific Proof: A 2018 study published in the Journal of Agricultural and Food Chemistry confirmed this mechanism, demonstrating significant improvements in vascular endothelial function.

Flavonoids like hyperoside and isorhamnetin enhance coronary blood flow and oxygen delivery to the heart muscle, strengthening the heart muscle itself while improving its endurance and pumping efficiency. This reduces cardiac workload while strengthening arterial elasticity and vascular integrity. By reducing the strain on the heart and improving its function, this ingredient supports longevity and helps protect against heart attack and stroke. Scientific Proof: A 2025 meta-analysis of six randomized controlled trials, including 428 participants, published in Pharmaceuticals, found a mean systolic blood pressure reduction of 6.65 mmHg after 2 to 6 months of use.

Holly Leaf improves blood fluidity by decreasing plasma viscosity and erythrocyte aggregation while increasing red blood cell deformability, allowing blood to flow more freely through even the smallest vessels. It also demonstrates dose-dependent reductions in total cholesterol, triglycerides, and LDL-C, helping to break down existing arterial plaque and prevent new build-up. This keeps arteries clear and flexible, reducing the risk of blockages that can lead to heart attack or stroke. Scientific Proof: A study in China Pharmacist confirmed these lipid-lowering and blood rheology benefits (P<0.05, P<0.01).

Fulvic acid acts as a powerful natural chelator, binding to bioactive compounds and essential minerals to transport them directly into cells. It delivers over 70 trace minerals and 22 organic acids that support mitochondrial energy production, neutralize free radicals, and dramatically enhance the absorption and efficacy of all other ingredients. This cellular nourishment supports brain health, cognitive function, and overall vitality, contributing to longevity and a healthier, more vibrant life. Scientific Proof: A 2015 University of Pretoria study demonstrated fulvic acid's ability to significantly increase mineral absorption through enhanced solubility and transport mechanisms.

Anyone who has survived a heart attack or stroke due to high blood pressure can tell you that it “just happens,” suddenly, without warning. You can feel entirely normal on any given day and then a sudden heart attack or stroke can leave you with at best a long hospital visit and at worst, as is unfortunately the case for many, death.

Yes! First-time customers can enjoy FREE shipping on their Alistrol order. Simply enter the code FREESHIP at checkout to save $29.95.

This offer is valid for U.S. and Canadian customers only. Due to higher international shipping costs and newly added tariffs, we as a company do not want our customers to incur extra expenses — so we’re covering that cost for you.

👉 Don’t forget to use FREESHIP at checkout to claim your savings.

All natural Alistrol is the world’s highest quality natural remedy to lower high blood pressure because all the ingredients are proprietary and grown on our own farms using our patented farming processes which provides the highest percentage in efficacy. This provides a consistent batch every time. In addition, the Alistrol proprietary formula is clinically tested and proven and provides heart health benefits. It increases the blood flow and oxygen flow to the heart muscle and all arteries.

All natural Alistrol is a non-prescription formula. If you are taking prescription, you may take all natural Alistrol in conjunction with your prescribed medication and wean yourself off the prescription in month 3 and only continue to take all natural Alistrol.

We ship to all English-speaking countries, including the United States, Canada, United Kingdom, Europe, Ireland, Australia, New Zealand and South Africa. If you are unsure whether or not we can ship to your country, please contact us for verification before placing your order.

Over 100,000+ satisfied customers. Fast shipment, in-stock product, great customer service, and high quality proprietary dietary supplements that work.

The high-quality solution can only be made from the purest ingredients. We oversee every step of the manufacturing process, from how we grow our herb crops to how our professional grade nutritional supplements are shipped out to you.
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We harvest the herbs in every single capsule at the peak of their growing season and under strictly controlled conditions to ensure consistent potency and purity. We are dedicated to the highest standards of quality assurance, from when the first sprouts break through the soil until the moment each bottle arrives at your home.

Alistrol is available online, by phone, and from select distributors worldwide. CLE Holistic Health's professional grade nutritional supplements are also distributed via Naturopathic and Chiropractic clinics across North America, Europe, UK and Australia. But we also ship to customers worldwide via our website.

Please allow between 5 - 7 business days for US and Canadian orders to arrive and between 7 -10 business days for international orders to arrive from date of order receipt.

Yes. If, for any reason, you are not completely satisfied with your purchase, simply return the unused/unopened bottles, within 90 days of your invoice date, for a full refund, minus shipping & handling charges: Returns Dept: Suite 345. 125A-1030 Denman St. Vancouver, BC V6G 2M6 CANADA.

The quickest and most effective method is to email us at info@cleholistichealth.com. You may speak with our friendly and courteous customer care representative’s by calling:
1-702-213-6382.

We accept Visa, Master Card, American Express and Paypal.

We understand many people are skeptical because most blood pressure supplements on the market use generic low-quality ingredients, ineffective dosages, or poorly absorbed formulations. Alistrol was developed differently using advanced farm-to-capsule botanical technology and clinically studied plant compounds designed to support cardiovascular wellness at multiple levels.

Unlike basic formulas that focus on only one ingredient, Alistrol combines synergistic botanical extracts with fulvic mineral infusion technology to support:

• Healthy blood flow
• Vascular flexibility
• Oxygen circulation
• Nervous system balance
• Heart muscle support
• Antioxidant protection

Farm-to-Capsule Technology
Since 2010, the botanical ingredients used in Alistrol have been cultivated directly on manufacturer-managed Canadian farms with strict quality-control standards from cultivation through extraction and encapsulation.

Health Canada Licensed
Alistrol is manufactured in a Health Canada licensed facility following strict manufacturing and quality-control standards.

Third-Party Tested
Every production batch undergoes third-party testing and Certificate of Analysis verification for purity, potency, and quality assurance.

Clinically Inspired Formulation
Alistrol was formulated using research-backed botanical ingredients studied for cardiovascular and circulation support.

Fulvic Mineral Infusion Technology
The fulvic mineral complex is designed to help improve nutrient transport and absorption, helping deliver bioactive plant compounds more efficiently throughout the body.

Alistrol was designed as a multi-pathway cardiovascular support formula:

• Hawthorn Berry Extract helps support vascular elasticity, circulation, and heart function.
• Daikon Seed Extract supports nitric oxide pathways involved in healthy blood flow and oxygen delivery.
• Garlic Extract contains sulfur compounds studied for cardiovascular and endothelial support.
• Holly Leaf Extract provides antioxidant and circulatory support.
• Fulvic Minerals help enhance nutrient absorption and cellular transport.

Together, these ingredients create an advanced synergistic superfood plant-based formula designed to support cardiovascular balance naturally.

Many users report that Alistrol feels more comprehensive compared to standard supplements because it focuses on the entire cardiovascular system rather than only one mechanism.

The formula supports circulation, oxygen flow, vascular relaxation, and nervous system balance together.

Alistrol has been trusted by over 100,000 customers seeking professional-grade cardiovascular wellness support.

Natural botanical formulations work progressively with consistent daily use.

Many users report improvements in circulation, energy, and cardiovascular wellness within 2-4 weeks as the ingredients support the body’s natural systems over time.